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gene: LDB2

id9079
symbolLDB2
organismHomo sapiens
full nameLIM domain binding 2
summaryThe protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
variant-disease

GRCh37/hg19 4p15.32(chr4:16518224-16575820)x1 AND not provided

GRCh37/hg19 4p15.32(chr4:15974221-16897124)x3 AND See cases

GRCh38/hg38 4p15.32(chr4:15868863-16925081)x1 AND See cases

GRCh37/hg19 4p15.32-15.31(chr4:16830399-17805183)x3 AND See cases

GRCh37/hg19 4p15.32(chr4:15836236-16942209)x3 AND See cases

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