GENETIC ENCYCLOPEDIA
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gene: SCT

id6343
symbolSCT
organismHomo sapiens
full namesecretin
summaryThis gene encodes a member of the glucagon family of peptides. The encoded preproprotein is secreted by endocrine S cells in the proximal small intestinal mucosa as a prohormone, then proteolytically processed to generate the mature peptide hormone. The release of this active peptide hormone is stimulated by either fatty acids or acidic pH in the duodenum. This hormone stimulates the secretion of bile and bicarbonate in the duodenum, pancreatic and biliary ducts. [provided by RefSeq, Feb 2016]
variant-disease

GRCh37/hg19 11p15.5(chr11:532230-699404)x3 AND See cases

GRCh37/hg19 11p15.5(chr11:532230-699463)x3 AND See cases

GRCh37/hg19 11p15.5(chr11:381754-821676)x3 AND not provided

GRCh37/hg19 11p15.5(chr11:556531-927020)x3 AND not provided

GRCh38/hg38 11p15.5(chr11:196855-2116185)x3 AND See cases

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