GENETIC ENCYCLOPEDIA
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gene: RXRG

id6258
symbolRXRG
organismHomo sapiens
full nameretinoid X receptor gamma
summaryThis gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
variant-disease

GRCh38/hg38 1q23.3-24.1(chr1:164547546-165689403)x1 AND See cases

GRCh37/hg19 1q23.3-24.2(chr1:163093021-168991239)x1 AND not provided

GRCh38/hg38 1q23.3-24.2(chr1:162040050-167480663)x1 AND See cases

GRCh38/hg38 1q23.3-25.1(chr1:163382523-175877022)x1 AND See cases

GRCh38/hg38 1q23.3-25.1(chr1:161740907-173965154)x1 AND See cases

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