GENETIC ENCYCLOPEDIA
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gene: MST1

id4485
symbolMST1
organismHomo sapiens
full namemacrophage stimulating 1
summaryThe protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq, Jan 2010]
variant-disease

NM_020998.3(MST1):c.55C>T (p.Pro19Ser) AND not provided

GRCh37/hg19 3p21.31(chr3:49723098-49728537)x3 AND See cases

GRCh38/hg38 3p21.31-14.3(chr3:49461000-55314500)x1 AND See cases

GRCh38/hg38 3p21.31-21.2(chr3:45879883-50749922)x4 AND See cases

GRCh37/hg19 3p22.2-21.31(chr3:37028313-49929220)x3 AND See cases

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