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gene: ICMT

id23463
symbolICMT
organismHomo sapiens
full nameisoprenylcysteine carboxyl methyltransferase
summaryThis gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]
variant-disease

GRCh37/hg19 1p36.31(chr1:6279370-6568387)x3 AND not provided

GRCh37/hg19 1p36.32-36.23(chr1:4965631-8106987)x1 AND not provided

GRCh37/hg19 1p36.32-36.23(chr1:2793822-7510850)x1 AND See cases

GRCh37/hg19 1p36.32-36.31(chr1:2609223-2631378)x3 AND See cases

GRCh38/hg38 1p36.32-36.23(chr1:2868477-7332569)x1 AND See cases

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