GENETIC ENCYCLOPEDIA
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gene: TRIM6

id117854
symbolTRIM6
organismHomo sapiens
full nametripartite motif containing 6
summaryThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010]
variant-disease

GRCh37/hg19 11p15.4(chr11:5485210-5719251)x1 AND See cases

GRCh37/hg19 11p15.4(chr11:5610674-6032001)x3 AND not provided

GRCh38/hg38 11p15.4(chr11:5593209-6447002)x3 AND See cases

GRCh38/hg38 11p15.4(chr11:3745061-7846057)x3 AND See cases

GRCh37/hg19 11p15.5-15.4(chr11:230615-9704511)x3 AND not provided

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